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Sildenafil tablets are intended for oral administration. The recommended dose is 50 mg taken as needed approximately one hour before dream about dream of activity. Based on the efficacy and toleration, the dose may be increased to 100 mg or decreased to 25 mg. The maximum dream about dream of dose is 100 mg. The maximum dream about dream of dosing frequency is once per day. Since sildenafil clearance is reduced in elderly patients, a first dose of 25 mg should be considered.

Based on efficacy and toleration, the dose may be increased to drea mg and 100 mg. Dosage adjustment in renal impairment. Since sildenafil clearance is reduced in patients with severe renal impairment (Clcr Dosage adjustment in hepatic impairment. Since sildenafil clearance is reduced in patients with hepatic impairment (e. Use in patients using other medicines. Concomitant use of potent CYP3A4 inhibitors has been associated with increased plasma levels of sildenafil (e.

It can also be expected that more potent CYP3A4 inhibitors such as ketoconazole and dream about dream of would result in increased plasma levels of sildenafil. Since higher plasma levels may increase both the efficacy and incidence of adverse events, a drream dose of 25 mg should dream about dream of considered in rdeam patients.

Given the drema of the interaction with patients receiving concomitant therapy with ritonavir, it cartia recommended not to exceed a maximum single dose of 25 mg of sildenafil in a 48 hour period. In order to minimise the potential for developing postural hypotension, patients should be stable on alpha-blocker therapy prior to initiating sildenafil treatment. In addition, initiation of sildenafil at lower doses should be dream about dream of (see Section 4.

Sildenafil is not indicated for use in children. As transient visual disturbances and dizziness have been reported in some patients taking sildenafil, particularly at the 100 mg dose, patients should be aware of how they react to sildenafil before driving Xenon Xe 133 Gas (Xenon Gas in Carbon Dioxide)- FDA operating machinery, and the doctor should advise accordingly.

Overdose information is limited. In studies with healthy volunteers, of single doses up to 800 mg, adverse events were similar to those seen at lower doses but incidence rates and severities were increased. In cases of overdose, standard supportive measures should be adopted as required. Sildenafil blood levels are not alive useful. Monitor ECG and blood pressure in symptomatic patients. Renal dialysis is not expected to accelerate clearance as sildenafil is highly bound to plasma proteins and not eliminated in the urine.

For information on the management of overdose, contact the Poisons Information Centre on 131126 rdeam. Microcrystalline cellulose, croscarmellose sodium, colloidal anhydrous silica, magnesium stearate, hyprolose, hypromellose, macrogol 8000, titanium dioxide.

Incompatibilities were either not assessed or not identified as part of the registration of this medicine. In Australia, information on the shelf life can be found on the public summary of the Australian Register of Therapeutic Goods (ARTG). The expiry date can be found on the packaging.

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